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DRIMEDEX™ – Clinical Strength Antiperspirant

Powerful, over-the-counter protection designed to help you fight excessive sweating — fast.

Drimedex delivers dermatologist-recommended ingredients at the strongest non-prescription strength available. Designed to help you stay dry and confident, even in extreme conditions.

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How to Use Drimedex

Why Drimedex Works

Unlike standard antiperspirants, Drimedex uses a high-potency aluminum salt compound that creates a temporary plug within the sweat ducts, significantly reducing perspiration at the source.

Stronger Ingredients

Formulated with the highest strength aluminum chloride allowed over-the-counter — for maximum dryness and fast results.

Precision Roll-On

Applies cleanly and targets underarms or problem areas with zero waste, zero mess.

Derm-Approved Science

Uses a formulation backed by decades of clinical research and trusted by dermatologists for patients with hyperhidrosis.

Clinical Evidence & Ingredients

Drimedex uses high‑strength aluminum chloride – a clinically validated compound that works by temporarily blocking sweat ducts. The metal ions precipitate with mucopolysaccharides inside ducts, forming plugs that prevent sweat from reaching the skin surface (PMC 3813027; International Hyperhidrosis Society) .

High‑Strength Formula

In a 15% aluminum chloride gel study, 72% of subjects achieved a clinically significant reduction in sweating by week 4 (Flanagan & Glaser 2009) .

Comparative Efficacy

20% aluminum chloride is considered the gold standard for axillary and palmar hyperhidrosis, showing ≥80% efficacy and long-term maintenance (IHS overview) .

Feature Drimedex Standard Antiperspirant
Active Ingredient 15–20% aluminum chloride 10–15% aluminum chlorohydrate
Sweat Reduction Up to 50–80% ~30–50%
Dermatology Tested Yes Yes

Frequently Asked Questions

Is Drimedex safe for daily use?

Yes. Drimedex is formulated using dermatologist-recommended concentrations of aluminum chloride that are safe for daily use when applied as directed. Most people apply it once daily, typically at bedtime.

Can I use this on my hands or feet?

Drimedex is designed primarily for underarm use, but may be applied to other areas such as hands or feet with caution. Avoid applying to broken skin and test a small area first to assess sensitivity.

What should I do if I experience irritation?

Mild irritation is uncommon but possible, especially on sensitive skin or with overuse. If irritation occurs, discontinue use temporarily and consult a healthcare professional. Never apply to freshly shaved or broken skin.

Is this the same as prescription Drysol?

Drimedex uses a similar high-strength aluminum chloride compound found in prescription products like Drysol, but is available over-the-counter. Many users report comparable effectiveness without the need for a prescription.

Important Information

What is Drimedex™?

Drimedex™ is a clinical-strength, over-the-counter antiperspirant designed to help reduce excessive underarm sweating. It contains dermatologist-recommended active ingredients that temporarily block sweat ducts to help minimize perspiration.

Drimedex is not intended to diagnose, treat, cure, or prevent any disease or medical condition, including hyperhidrosis. It is not a prescription medication and is for external use only.

Warnings & Usage Notes

  • For external use only. Do not apply to broken, irritated, or freshly shaved skin.
  • Discontinue use if irritation or rash develops. If symptoms persist, consult a healthcare professional.
  • Not recommended for use on the face, groin, or mucous membranes.
  • Keep out of reach of children. If swallowed, get medical help or contact a Poison Control Center right away.
  • Use only as directed. Apply at night to clean, dry underarms and wash off in the morning.

Consult Before Use If You:

  • Have a history of skin sensitivity or allergic reactions to topical products
  • Are pregnant or breastfeeding
  • Have persistent or unexplained sweating (which may require medical evaluation)

Disclaimer: The information provided on this site is for general informational purposes only and is not a substitute for medical advice. Always follow label directions. Individual results may vary.